Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Researchers reveal that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and ...

Three water-soluble egg yolk fractions (FA, FB, and FC) and subfractions of FC (FC1 (< 3 kDa) and FC2 (> 3 kDa)) showed promising osteoclastogenesis inhibitory effects by suppressing osteoclast ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts. This ...

A team from the Medical University of Vienna, in Austria, has successfully developed an algorithm within the StrataQuest image analysis software that can automatically detect and quantify osteoclasts.

Female ginseng has long been used in traditional Chinese medicine for osteoporosis treatment. A new compound that affects osteoclast formation has been derived from the plant Angelica sinensis, ...