Figure 1: A fluorescence image of an induced presomitic mesoderm (iPSM) tissue model, where cells expressing the Hes7 gene—a key regulator of somite formation—are ...

Scientists have uncovered a surprising new way that giant embryonic cells divide—without relying on the classic “purse-string” ring long thought essential for splitting a cell in two. Studying ...

S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 ...

Study finds that large embryo cells divide step by step using a mechanical ratchet system, challenging the textbook idea of a ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...

New stem cell-based embryo model reveals previously unknown communication between early tissues that become the spine and muscles in the central part of the body. From the moment an embryo starts to ...