Discovering and bringing a new drug to market typically takes 14 years and costs approximately $ 2 billion USD. Today, the competitive landscape throughout the drug development process requires ...
Preclinical characterization of drug disposition generally involves the assessment of individual proteins for their role in the disposition of the NCE. A summary of currently available tools for such ...
To evaluate the SimCYP simulator ethnicity-specific population model for predicting the pharmacokinetics of midazolam, a typical CYP3A4/5 substrate, in Chinese after oral administration. It is ...
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