近日，中南民族大学生物医学工程学院阳小飞教授团队在神经科学顶级期刊 Nature Neuroscience 上发表了题为 Munc18 modulates syntaxin phase separation to promote exocytosis 的研究论文 。该研究首次揭示，神经元突触前膜中的关键蛋白 syntaxin 可通过“液 - 液相分离”形成动态聚集，并受到 Munc18 ...

Video - Compilation of protein condensate formation. Full video available from Supplementary Information of the original article .

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Crystallization is a well-explored natural phenomenon where atoms or molecules arrange themselves into highly organized solid forms called crystals. This phenomenon has been widely utilized across ...

In mammalian cells, besides nuclei, mitochondria are the only semi-autonomous organelles possessing own DNA organized in the form of nucleoids. While eukaryotic nuclear DNA compaction, chromatin ...

Researchers used cloud point measurements to construct a phase diagram. The solid lines represent the droplet density, while the dashed lines represent the solution density. Crystallization is a ...

Phase separation in nuclear cell biology represents a conceptual framework for understanding how cells spatially and temporally regulate gene expression.