For the picoPSU-150-XT you can just buy a smaller power brick more suited to your load, not sure if that would help efficiency or not (I forget what the DC-DC curve looks like on the picoPSU). However ...

Tiny picoPSU Power Supply Enables Design of Small, Quiet PCs and Smart Appliances; Gives Robots More Freedom to Roam World’s tiniest PC power supply offers new design possibilities for PCs, case mods ...

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The picoPSU-120 12V DC-DC ATX PSU isn't your typical PSU as the "120" implies. Nonetheless, this is an ingenious little device is rated at 120 Watts and can handle a max load of 140 watts to your ...