Aged haematopoietic stem cells (HSCs) generate more myeloid cells and fewer lymphoid cells compared with young HSCs, contributing to decreased adaptive immunity in aged individuals. However, it is not ...

Figure 1: vWF–eGFP-expressing platelet-biased haematopoietic stem cells. Unless otherwise stated, data are presented as mean ± s.e.m. values. Two-tailed Student’s t-tests were used to assess ...

Future Microbiol. 2013;8(11):1431-1451. Bacterial contact with the platelets is a key event for the pathogenesis of sepsis, as deduced from the correlation between sepsis outcome and decreased ...

As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don’t need to and can cause major issues such as strokes and cardiovascular ...

SAN DIEGO, Dec 10 (Reuters) - Scientists have for the first time created blood platelet cells by reprogramming stem cells derived from adult cells, offering the potential for a renewable supply of the ...

Researchers have discovered a distinct, secondary population of platelets that appears with aging and have hyperreactive behavior and unique molecular properties, which could make them easier to ...

Platelets are components of blood best known for their role forming clots that stop bleeding. But Watertown, Massachusetts-based PlateletBio notes that platelets have other properties, including a ...

SAN DIEGO (Reuters) - Scientists have for the first time created blood platelet cells by reprogramming stem cells derived from adult cells, offering the potential for a renewable supply of the fragile ...

Despite being acaryote cell fragments, platelets share a number of properties of host defense with their big nucleated relatives and represent important elements in innate immunity. For these purposes ...

When a vascular injury occurs, platelets in young mice form much smaller blood clots (left) than platelets in old mice (right), where the clot almost blocks the blood vessel. Fluorescence microscopy ...

Cancer researchers report that blood platelets blunt the immune response to cancer. Genetic inactivation of platelets improved the ability of T cells to fight melanoma in preclinical tests. Adoptive T ...

Platelets are small, disk-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury. Platelet transfusions in patients with severe trauma or ...