Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...

A pore smaller than one nanometer reads peptide sequences amino acid by amino acid, pinpointing single-site Alzheimer's ...

Scientists and engineers have long been interested in synthesizing peptides — chains of amino acids responsible for conducting many functions within cells — to both mimic nature and to perform new ...

Scientists have developed a way of finding optimal peptide sequences: using a machine-learning algorithm as a collaborator. The algorithm analyzes experimental data and offers suggestions on the next ...

In a pair of cross-appeals from the International Trade Commission, the Federal Circuit affirmed the Commission’s ruling that one of CJ CheilJedang Corp.’s engineered bacterial strains infringed ...

Thymagen has emerged as a notable compound in contemporary peptide science due to its structural relationship to ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

The World Health Organization estimates that antibiotic resistant infections kill more than a million people worldwide every year, so many researchers are actively looking for new ways to combat it.

Fibrous structures act as load-bearing components in vivo in many natural proteins besides enzymes, which are soluble globular molecules. Natural evolutionary processes have produced structural ...