BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels—which open only when a specific voltage is reached across the cell ...

Researchers have revealed how a channel that controls cellular potassium levels causes metabolic rewiring in breast cancer cells, promoting tumour growth. Researchers have revealed how a channel that ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

This article and associated images are based on a poster originally authored by Sivakumar, M, Smith, E, Shumate, J, Scampavia, L, Spicer, T, Hernandez, D and Peters, C and presented at ELRIG Drug ...

Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer. Scientists at The Hospital for Sick Children (SickKids) have ...

Walter and Eliza Hall Institute scientists have made a significant advance in understanding how potassium channels, which permit the flow of electric currents central to many of the body's biological ...