Efficient buffer preparation is vital in biomanufacturing, requiring careful consideration of various factors to meet the evolving needs of modern therapeutics. In addition to considerations about ...

This lab includes the complete titration procedure used to investigate how well a buffer resists changes in pH. Prepare a buffer solution by accurately calculating and measuring the required amounts ...

Antibodies are subject to instability issues due to chemical and physical instabilities and these effects can change the pharmacokinetics of the antibody. For this reason, produced antibodies must be ...

Figure 2: Representation of the 96-well microplate used in this protocol. This material is hazardous when in contact with eyes, skin or respiratory system. Wear goggles, lab coat and face mask during ...

Recently, the trend of outsourcing buffer manufacturing system has been adopted by pharmaceutical companies as it reduces the cost of buffer formulation, eliminates space and temperature maintenance ...

This lab includes a theoretical explanation of how buffers work and how they are made, including a derivation of the Henderson-Hasselbalch equation. Students will use what they have learned to ...

Managing buffers in bioprocessing remains a largely manual process, requiring space and resources and often creating bottlenecks that increase costs and decrease efficiency. Researchers from many of ...