Studies have demonstrated a critical role of the cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25, produced by epithelial and other cells at mucosal surfaces in response to a wide range ...

Researchers identify specific immune markers, like activated monocytes and cytokines, that drive cognitive decline after viral infections across various diseases.

CRISPR/Cas-based biosensors offer an opportunity to quantify neuroinflammation in Parkinson’s disease, advancing diagnostics ...

Pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) are produced in large quantities locally in the joints and subsequently enter the bloodstream. TNF-α and IL-6 may promote LDL metabolism by ...

(a) Gluten is ingested and digested, reaching the gut lumen as gliadin peptides; (b) Gliadins are a prime substrate for deamidation and cross-linking by luminal transglutaminases. These ...

Autoimmune diseases stem from a complicated interplay of immune dysregulation, characterized by chronic inflammation and the loss of self-tolerance. Cytokines are central to these processes. These ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

Rheumatoid arthritis (RA) is a common autoimmune disease in which the immune system recognizes autoantigens on otherwise healthy joint tissues as foreign invaders, inducing a localized inflammatory ...