Cells assemble protein networks through regions of protein recognition that are found in numerous proteins as conserved peptide motifs. This allows for the specific and efficient communication of ...

Researchers found a rare example of an ancient protein that can still function in a molecular mirror world – offering new clues about the evolutionary history of proteins that bind to nucleic acids.

Only recently appreciated as critical components of cellular functions, unstructured stretches of amino acids called SLiMs are key to viral-host interactions. During an early COVID-19 lockdown in ...

In a recent study posted to the bioRxiv* preprint server, researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) ...

Viruses frequently produce host protein mimics to stall or exploit cellular machinery within the replication cycle, and many such protein motifs have evolved to the capacity to enhance immune evasion.

A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that the motif can interact with both natural and mirror-image nucleic acids, an ...

LA JOLLA, CA— Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and ...