引言我们习惯于将细胞内的分子赋予明确的角色分工。基因是蓝图，蛋白质是执行者，而代谢物（Metabolites）——那些在生化反应中流转的小分子，往往被视为燃料、建筑模块，或者是信号通路中的信使。然而，当我们认为已经掌握了细胞运作的基本逻辑时，生命总会 ...

RNA splicing involves the removal of non-coding introns and the joining of coding exons in precursor mRNA (pre-mRNA) to produce mature messenger RNA (mRNA). Splicing changes can lead to diseases, ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...

Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have ...

Researchers uncovered how polyamines influence cell fate by altering protein phosphorylation and alternative splicing. The ...

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses ...

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the ...

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as ...

Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...