RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...

Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...

RNA病毒是遗传多样性最丰富、进化速度最快的一类微生物，能够引发多种人类、动物和植物感染性疾病，对全球公共卫生与生物安全构成持续威胁。解析RNA病毒蛋白的三维结构，是理解病毒感染与免疫逃逸机制、指导抗病毒药物和疫苗研发的关键基础。然而，受限于蛋白结构解析技术等因素的限制，目前实验解析的RNA病毒蛋白结构仍然 ...

Researchers engineered the first RNA-based NAND gate in living cells using deep learning and Bayesian optimization, testing ...

With AI, it's now possible for researchers to predict the three-dimensional structures of proteins directly from their ...

Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

Tina de los Reyes is the strategic biopharma development specialist for the Western US. With over 10 years of commercial experience in NGS and a Masters in Biomedical diagnostics, she specializes in ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

The influenza virus continues to pose a threat to our health. It triggers seasonal epidemics and, from time to time, potentially serious global pandemics. Existing antiviral drugs are often less ...

Rutgers University–Newark researchers have developed a first-of-its-kind RNA nanotechnology. The development self-assembles inside living human cells and can be programmed to halt the growth of ...