A group of interdisciplinary Boston University researchers worked together to investigate the promising technology of self-amplifying RNA as a way to deliver lifesaving drugs and create more effective ...

Viruses are entities that have to infect other cells in order to replicate. They may have genomes that are made of DNA or RNA. We are still discovering new types of RNA viruses, as shown in two new ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...

Endogenous RNA is central to protein control and, ultimately, cellular function. Synthetic RNA is an important tool for biological research and is also offering a new generation of promising ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine.

This work presents a redox-responsive strategy for precise RNA control via post-synthetic 2′-OH acylation. These introduced disulfide-containing acyl groups can be selectively cleaved upon exposure to ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...

Northwestern University in Illinois, US, has announced a new method for detecting RNA modification patterns in blood samples that could enhance early colon cancer detection. This was detailed in a ...