PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

Once overlooked, astrocytes are increasingly recognized as star players in Alzheimer’s disease, with recent studies blaming them for feeding into a neurotoxic stew that kills neurons. In the September ...

Astrocytes, the predominant glial population in the human central nervous system, play crucial roles in neuroprotection, immunity, and homeostasis. However, when exposed to certain neuroinflammatory ...

Why do some people with amyloid plaques decline, while others do not? In the May 29 Nature Medicine, researchers led by Tharick Pascoal at the University of Pittsburgh laid some of the blame on ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

The selective MAOB inhibitor KDS2010 significantly improved functional recovery in a spinal cord injury animal model. Treated animals showed marked restoration of behavioral scores and locomotor ...

Much of the brain is made up of a constellation of star-shaped cells called astrocytes, which play vital roles in immunity, neuron maintenance and many other functions. In Alzheimer’s disease, some ...

When the brain is injured in some way, a wide range of biochemical changes are triggered that can affect crucial brain cells known as astrocytes. They are a type of glial cell, and brain injuries ...

Researchers have discovered the mechanism by which a cluster of astrocytes, specialized brain cells, in the hypothalamus cause obesity in mice. Their study also identified a drug that inhibited the ...