A receptor involved in normal physiological processes may also drive breast cancer growth when overexpressed.

(seen here from above) has three parts. If activated, a pore in the receptor opens and allows ions to flow into the cell. PSB-0704 (shown in color) prevents this from happening and blocks, for example ...

The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered ...

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited. The human P2X4 receptor plays an important role in chronic ...

The research, published June 4 in Nature Structural & Molecular Biology, identifies critical connections between activity of the epilepsy drug perampanel and the resulting movements of the AMPA ...

A protein, the farnesoid X receptor, that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another protein, but new research shows it can also work ...

Researchers hope to undertake clinical studies in multiple cancers, including ovarian cancer, glioblastoma, and others.

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes ...

MOUNTAIN VIEW, Calif.--(BUSINESS WIRE)--Olfactive Biosolutions, a leader in ectopic and chemosensory receptor technology, recently filed a U.S. patent for Protenx, a proprietary line of breakthrough ...