A receptor involved in normal physiological processes may also drive breast cancer growth when overexpressed.

(seen here from above) has three parts. If activated, a pore in the receptor opens and allows ions to flow into the cell. PSB-0704 (shown in color) prevents this from happening and blocks, for example ...

The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered ...

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited. The human P2X4 receptor plays an important role in chronic ...

The research, published June 4 in Nature Structural & Molecular Biology, identifies critical connections between activity of the epilepsy drug perampanel and the resulting movements of the AMPA ...

Researchers hope to undertake clinical studies in multiple cancers, including ovarian cancer, glioblastoma, and others.

Researchers examine the thermodynamic properties of the interaction of the histamine H1 receptor with geometric isomers of the antihistamine drug doxepin Recently, the importance of drug design based ...

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...

A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

MOUNTAIN VIEW, Calif.--(BUSINESS WIRE)--Olfactive Biosolutions, a leader in ectopic and chemosensory receptor technology, recently filed a U.S. patent for Protenx, a proprietary line of breakthrough ...