来自伊利诺斯大学厄尔本纳-香槟分校分校,霍德华休斯医学院等处的研究人员研发了一种新型蛋白分析技术,能帮助研究人员获得胞内单一蛋白复合物的直观图像,这种称为SiMPull(single-molecule pull-down)的方法能帮助科学家们更深入的分析各种体内蛋白。
本刊推荐:本研究运用单分子下拉技术(SiMPull)结合超分辨显微镜(dSTORM)和蛋白质组学,首次在单粒子水平实现对运动神经元病(MND)患者脑组织中TDP-43聚集体的定量表征。研究发现疾病特异性聚集体具有更长尺寸、更高纤维化程度和更低抗体标记密度的纳米 ...
Proteins perform most cellular functions in macromolecular complexes. The same protein often participates in different complexes to exhibit diverse functionality. Current ensemble approaches of ...
Factory-installed SIMpull Head pulling grips eliminate the process of making up pulling heads as well as the risks of knife cuts and other injuries from exposed wire or scrap. The recyclable grips ...
Southwire introduces SIMpull® Cable-in-Conduit for utility customers as the first certified SIMpull Solutions® product developed for the energy industry. Southwire SIMpull Solutions products and ...