Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps explain a ...

Adding to the growing fundamental understanding of the machinery of muscle cells, a group of biophysicists describe -- in minute detail -- how actin filaments are stabilized at one of their ends to ...

Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) developed a mouse model that enables them to look inside a working muscle and identify the proteins ...

Thick filament structure in the relaxed cardiac sarcomere. The upper image shows a tomographic slice of a cardiac sarcomere. Thin filaments are marked with a green and thick filaments with a purple ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Alveolar rhabdomyosarcoma is a cancer of the muscle lineage. Cancer Cachexia is a muscle and fat wasting syndrome associated with cancers of the pancreas, lung, colon. Nemaline myopathy is associated ...