Figure 1: Generation of procoagulant activity in human blood by P-sel–Ig is mediated by PSGL-1. Figure 2: Recruitment of fluorescent microparticles into a growing thrombus. To evaluate whether ...
本研究通过整合29项观察性研究的荟萃分析和孟德尔随机化(MR)方法,首次系统证实内皮功能障碍蛋白vWF和E-selectin分别与心源性栓塞性卒中(CES)和大动脉粥样硬化性卒中(LAS)存在因果关联,为缺血性卒中(IS)亚型特异性防治策略提供了分子靶点。 缺血性卒中作为全球 ...
这篇综述系统阐述了选择素(Selectins)在动脉粥样硬化(AS)中的多维度作用机制,突破性地将其从传统黏附分子重新定义为 ...
Peripheral blood (approximately 0.5 mL) was obtained by venipuncture, placed in a heparinized tube, and immediately transported on ice to the laboratory for processing. Processing was accomplished ...
Memory T lymphocytes extravasate at sites of inflammation, but the mechanisms employed by these cells to initiate contact and tethering with endothelium are incompletely understood. An important part ...
Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall shear stress is ...
Selectins are required for the trafficking of innate immune system cells, T lymphocytes and platelets. The absence of selectins or their ligands has severe health ...
Dynamics of growth of transplantable sarcoma 45 (S45) in injection of autologous and allogenic serum. Dynamics of IGF-I, IGF-II and TGF-β1 in lung and liver in the early stages of metastasis in ...
In a surprising discovery, a ‘sticky molecule’ that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new ...
In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new ...
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