Familial pure dominant spastic paraplegia (SPG) is a clinically and genetically heterogeneous group of neurodegenerative disorders, mainly characterised by spasticity of the lower limbs. Gait ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders that are mainly characterised by progressive spasticity and weakness of the lower limbs. Recent ...

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Since she was born 20 years ago, Sylva Eugenie Davis of Kansas City has not been able to use her arms or legs. The nerve tracts in the neck region of her spinal cord were injured at birth, causing ...

(Philadelphia, PA) – While it might have given our ancestors an evolutionary advantage, an "unstable" region on human chromosome 15 is also the source of a set of inherited neurological diseases.

A joint study conducted by the University of Bonn and the DZNE has confirmed early-stage brain inflammation in mice. Patients with spastic paraplegia type 15 develop movement disorders during ...

The Qiang Laboratory concentrates on using human induced pluripotent stem cell (hiPSC) based technologies to establish in vitro (distinct phenotypical CNS neuronal cultures) and ex vivo (3d forebrain ...

There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved ...

Spastic limb paralysis due to injury to a cerebral hemisphere can cause long-term disability. We investigated the effect of grafting the contralateral C7 nerve from the nonparalyzed side to the ...

MATTOON (JG-TC) -- The Spastic Paralysis Research Foundation board chairman is scheduled to give a presentation during the Mattoon Kiwanis Club meeting on Wednesday. The Mattoon club reported that ...