Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...

There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved ...

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., ...

Hereditary spastic paraplegias (HSP) are a group of hereditary diseases that result in progressive loss of motor function in the lower limbs, and mutations in many different genes have been implicated ...

Boston Children’s Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., ...

NASHVILLE, Tenn. (WKRN) – Imagine losing the strength in the muscles of your legs and not knowing why. The condition is often misdiagnosed and worsens with time. It’s a rare reality for about 20,000 ...

In a recent publication in Molecular Therapy, researchers from Drexel University College of Medicine and UMass Chan Medical School presented a silence-and-replace gene therapy strategy aiming to ...

Mike Wolanin | The Republic Kyle Alumbaugh demonstrates how he uses his wheelchair ramp participate in 5k run, walk or roll to raise awareness for Hereditary Spastic Paraplegia and Primary Lateral ...

A disease-causing gene in hereditary spastic paraplegia bolsters the theory of altered lipid processing as a shared cause in motor neuron diseases. Genetic and cellular studies, led by Andrew Crosby ...