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4 个月
小鼠莱迪希细胞系TM3和MLTC-1的分子特征分析
本研究系统比较了两种常用Leydig细胞(LC)永生化模型TM3和MLTC-1的分子特征与功能响应,发现TM3细胞缺乏Lhcgr受体表达且对hCG无应答,无法激活甾体生成通路,而MLTC-1细胞具有激素响应能力并表达关键酶基因。通过形态学(电镜、F-actin染色)、转录组测序和STR分 ...
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