Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Explore how claudin-18.2 can transform cancer treatment for gastric and pancreatic tumours using targeted radiotherapy.

Neuroimmune diseases, such as multiple sclerosis, myasthenia gravis, and autoimmune encephalitis, are debilitating conditions ...

Targeted therapies are cancer medications that work more selectively than standard chemotherapy medications. They do this by targeting specific molecules or genetic changes in cancer cells in order to ...

PI3K signaling pathways. Upon activation by RTK, GPCR, Integrin, and Ras, p110 loses inhibition by p85 and converts PIP2 to PIP3. PIP3 recruits AKT to the cell membrane, where AKT is activated through ...

A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights ...

Phase 1b study to evaluate combination of zongertinib and zanidatamab in HER2-positive breast cancer patients Ingelheim, Germany-- 12 January, 2026 -- Boehringer Ingelheim today announced a strategic ...

Breakthrough Therapy Designation granted to zoldonrasib for the treatment of adult patients with KRAS G12D-mutated locally advanced or metastatic ...

Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. So we used to think as, asthma is asthma, ...