Researchers reveal that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and ...

Elevated tryptophan metabolism correlates with improved csDMARD response, reduced inflammation, and better clinical outcomes in rheumatoid arthritis patients. Multiomics analysis identified ...

As people grow older, the same brain chemistry that once supported sharp thinking and stable mood can quietly start to work against them. A new wave of research is revealing how a single amino acid, ...

Microbiome dysbiosis—changes in the composition of gut microbes that alter the metabolites present—has long been implicated in playing a causative role in the pathophysiology of autism spectrum ...

In research published in the journal Gut, investigators from the University of Alabama at Birmingham report that restoring tryptophan metabolism in the gut microbiome can prevent or reverse diabetic ...

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the ...