A type of circular DNA called extrachromosomal DNA was thought to be found exclusively in cancer. Its discovery in non-cancerous tissue suggests that it might have an early active role in malignant ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Scientists have found that twisting structures in DNA long mistaken for knots are actually something else entirely. Inside cells, DNA gets twisted, copied, and pulled apart. The twists can influence ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...