Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and ...

To navigate, the brain must convert changing sensations into a map-like sense of the world, which remains stable as the body moves. A new study finds that the fly brain sometimes performs the ...

image: New research shows that somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex ...

WEST LAFAYETTE, Ind. - A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in ...

Combined experimental and theoretical tools that include biochemical and molecular biology approaches, genome, transcriptome, and proteome analyses, and comparative methods, have advanced our ...

The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism. “There is a problem of timing, ...