Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report researchers. Crucial to cilia ...

A global research collaborative including Medical University of South Carolina investigators report in today's Science Translational Medicine that defects in the primary cilia of the developing fetus ...

Heart valve defects are a common cause of death in newborns. Scientists have discovered "Creld1" is a key gene for the development of heart valves in mice. The researchers were able to show that a ...

EUGENE, Ore. -- May 5, 2016 -- A cell-to-cell signaling network that serves as a developmental timer could provide a framework for better understanding the mechanisms underlying human heart valve ...