高脂饮食诱导的肠道菌群失调促进代谢相关脂肪性肝病（MAFLD）向肝细胞癌（HCC）进展，其机制涉及肠道致病菌Enterococcus faecalis抑制肝脏IGSF9表达，导致C1q异常积累，加剧脂质浸润、炎症和纤维化。补充益生菌Bifidobacterium pseudolongum或中和C1q抗体可有效逆转上述 ...

研究 Enterococcus faecalis 在铁暴露及谷胱甘肽缺乏条件下的代谢与转录响应，发现 Δgsh 突变体通过降低铁含量、激活尿素循环和甘油代谢补偿谷胱甘肽不足，维持生长。基因组模型显示 arginine 代谢（arcoperon）和能量生成途径是关键补偿机制，且转录因子 ArgR 的调控 ...

Researchers found that a common antibiotic-resistant bacterium prevents wounds from healing by chemically paralyzing skin cells rather than attacking them directly. Scientists from an international ...

Singapore scientists have found a new way to disarm antibiotic-resistant bacteria and speed up chronic wound healing using ...

Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a ...

A new study finds that two subtypes of pathogenic Escherichia coli (E. coli) produce five to 16 times more protective capsular “slime” when Enterococcus faecalis (EF) is present. The finding could ...

A new study finds that two subtypes of pathogenic Escherichia coli (E. coli) produce five to 16 times more protective capsular 'slime' when Enterococcus faecalis (EF) is present. The finding could ...