CRISPR文库筛选新突破：揭秘自闭症与脑发育机制，锁定 PEDS1 致病基因 ...

神经发育障碍（NDDs） 涵盖自闭症、智力障碍等多种疾病，其核心源于脑发育过程的分子调控紊乱，但多数致病基因和通路仍未被解析。耶路撒冷希伯来大学、欧洲勃艮第大学和里昂克劳德伯纳德大学通过 全基因组CRISPR敲除文库筛选 ...
腾讯网

Cell Stem Cell：清华大学李寅青/张学工团队揭示CRISPR基因编辑存在新 ...

编辑丨王多鱼排版丨水成文CRISPR-Cas9 基因编辑技术为遗传疾病的治疗带来革命性突破，FDA 已批准了基于 CRISPR-Cas9 的基因编辑疗法 Casgevy 用于治疗镰状细胞病（SCD）和 β-地中海贫血（TDT）。之前对于其安全性的研究，通常聚焦于脱靶效应引发的基因组序列改变，往往忽视了其对细胞表观基因组及其功能的影响。2026 年 ...

喝杯咖啡或帮助抗癌？华人团队打造咖啡因+CRISPR黑科技，能激活体内 ...

每天早上喝的那杯咖啡，也许有一天可以帮你抗癌。近日，美国德州农工大学周玉斌（音）教授和团队将咖啡因和 CRISPR 基因编辑技术结合起来，造出了一种可以被咖啡环唤醒的治疗系统。简单来说，未来医生可能在你体内植入一些经过设计的细胞，然后你只需要喝杯咖啡，这些细胞就会开始干活，比如释放胰岛素，或者激活免疫细胞去攻击肿瘤。 这个系统的核心是一种叫做化学遗传学的技术。该团队先在体外使用基因工程改造一批细胞 ...
STAT

Biotech investors: Stop expecting CRISPR science to make big leaps

Banas is associate director of research at the Gene Editing Institute at ChristianaCare, where Kmiec is founder and executive director. The medical promise of CRISPR gene editing can be seen most ...
STAT

The race to build better CRISPR delivery vehicles is heating up

If the first CRISPR decade was marked by a mad dash to evolve, engineer, and mine the bacterial universe for more and better genome-editing enzymes, so far the second seems to be all about three words ...
Yahoo

AI-powered CRISPR technology turbocharges gene therapy development

Add Yahoo as a preferred source to see more of our stories on Google. Stanford researchers have developed CRISPR-GPT, an AI-powered copilot that guides gene-editing experiments. (CREDIT: Shutterstock) ...
The Motley Fool

Could CRISPR Therapeutics Become the Next Vertex Pharmaceuticals?

CRISPR Therapeutics and Vertex Pharmaceuticals are partners in one particular program, and they recently won approval for the gene-editing treatment Casgevy. Beyond Casgevy, Vertex has a ...
Nasdaq

Is CRISPR Therapeutics Stock a Buy?

At the moment, CRISPR Therapeutics (NASDAQ: CRSP) is in a special period that most biotechs never survive to reach. Small groups of patients are now being treated with its first medicine to reach the ...