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生物通
10 年
Science提出免疫耐受新概念
起源于胸腺,自身免疫调控因子(Aire)蛋白控制了一个阻止免疫系统攻击自身身体的关键机制。个体的T细胞可攻击不同的物质;Aire通过生成一个mRNA转录物库,编码机体一些分化细胞类型特征性的蛋白质促进了免疫耐受。源自这些蛋白质的肽显示在胸腺髓质上皮 ...
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