The HIV-1 envelope, gp120, which features the binding determinants for both CD4 and coreceptor recognition, is key for virus entry and represents an attractive pharmacological target. However, ...

Glycoconjugate vaccines can spur the body’s immune system to seek out and attack pathogens or cancer cells on the basis of which specific sugar chains decorate those targets. Approved vaccines for ...

Conventional wisdom says that the scaffold in an important class of biological molecules called 'glycoconjugates' is essentially inert. Work by a chemist suggests otherwise. The discovery opens up new ...

Researchers have created a vaccine that is more potent than traditional vaccines available today. The glycoconjugate vaccine prototype is 100 times more effective than traditional glycoconjugate ...

Our cells live in a carbohydrate jungle. In particular, stem cells interact with a forest full of sugars, which trigger how they grow and differentiate. But when scientists grow stem cells in the lab, ...