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生物通
3 个月
整合网络药理学和机器学习研究确定NLRP3是赖氨酸在急性心肌梗死 ...
心肌梗死(AMI)的复杂病理机制及莲心碱(liensinine)的潜在保护作用研究。通过整合网络药理学、机器学习算法(LASSO、SVM-RFE ...
生物通
8 个月
莲心碱通过AMPK-HIF-1α轴重塑肝癌免疫微环境并增强免疫治疗的代谢 ...
本研究针对肝细胞癌(HCC)治疗困境,通过天然生物碱莲心碱(Liensinine)调控AMPK-HIF-1α信号轴,揭示其通过诱导内质网应激(ER stress ...
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