Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), ...

A previously unidentified physically activated pathway for cellular uptake in the body’s immune defence system could predate commonly recognized receptor-mediated processes. The pathway relies on ...

IBEC’s Principal Investigator César Rodriguez-Emmenegger has been awarded an ERC Consolidator Grant to develop Phagocytic Synthetic Cells (PSCs) to fight antibiotic-resistant pathogens. César ...

T Cells Gain Phagocytic Function via Specific Antigen RecognitionThe research team engineered CD8+ Jurkat T cells to express SVAR16 ...

As microbes invade the human body, phagocytic cells such as macrophages spring into action to clear the intruders. These cells extend arm-like projections and wrap them around the microbes before ...

Suppressing CD33 stimulates phagocytosis, slows plaque growth. A protective CD33 mutation could be a gain of function that activates phagocytosis. The CD33 receptor acts as a dimer. At the 14th ...

The coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 4.9 million deaths worldwide, as well as a significant ...

Phagocytosis is a key mechanism for removing apoptotic cells and intruders. While this process is essential to maintain tissue homeostasis and immune function, researchers have limited technologies to ...

Microglia tend to get off-kilter in Alzheimer’s and other neurodegenerative diseases. Now, researchers in Tony Wyss-Coray’s lab at Stanford University believe they have discovered a means of restoring ...

Phagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have ...

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E210-E217. doi: 10.1073/pnas.1716055115. Epub 2017 Dec 26.