Enhanced chromosomal radiosensitivity has been observed in a large number of patients with cancer-prone genetic diseases such as ataxia–telangiectasia and Nijmegen breakage syndrome (Gatti, 2001).

Mechanism of radiosensitivity of normal tissues, a key factor in determining the toxic side effects of cancer radiotherapy, is not fully understood. We recently demonstrated that deficiency of ...

It is often unknown whether a patient will respond to a treatment until it is in full swing. New research is attempting to identify chemo and radiosensitivity mechanisms in cancers and how to use them ...

Impact on U251 glioma cell radiosensitivity and CFL1 level via inhibiting cell motility regulator ROCKII of RhoA-RockII-CFL1 pathway.

The prognostic impact of CD3, CD8, FoxP3, and IL17 tumor-infiltrating immune cells in periampullary cancer differs by morphological type and adjuvant chemotherapy. This is an ASCO Meeting Abstract ...

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge. The present study delves into the role of ...

A new study found that the degree of immune enrichment predicted radiosensitivity. The radiosensitivity index (RSI), a validated genomic marker, was higher in pretreatment immune-enriched ...

GENEVA, Switzerland — Increased radiosensitivity likely contributes to improved outcomes in patients human papillomavirus (HPV)-positive head and neck squamous cell carcinomas (HNSCC), according to a ...

If you would like to learn more about the IAEA’s work, sign up for our weekly updates containing our most important news, multimedia and more. INTERNATIONAL ATOMIC ENERGY AGENCY, Genetical Aspects of ...

Researchers have validated a radiosensitivity molecular signature that can lead to better radiation therapy decisions for treating patients with breast cancer. Researchers at Moffitt Cancer Center, ...