Tissue changes of chronic gouty arthritis have been ascribed to deposition of monosodium urate (MSU) microcrystals and inflammation. The hallmark of chronic gout are intraarticular and periarticular ...

The characteristics of the sample are presented in Table 1 and Table 2. The average age was 60.9 years, and patients had been diagnosed an average of 12 years. Most were male (81%), and 38% were ...

Background: The prevalence of gout is increasing, and most research on the associated burden has focused on serum urate (sUA) levels. The present study quantifies the impact of the presence of tophi ...

The advanced imaging method dual-energy CT (DECT) has been found to be a reliable measure of tophus size and composition in patients with gout, according to new research published in Journal of ...

The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...

Un-calcified tophaceous deposits that were undetected with conventional radiography may be visible on musculoskeletal ultrasound, according to recently published data. Researchers evaluated 24 ...

Please provide your email address to receive an email when new articles are posted on . Both excessive and long-term alcohol consumption, as well as any spirit consumption, predict the development of ...

SAN DIEGO, Aug. 20, 2025 /PRNewswire/ -- Arthrosi Therapeutics, Inc., a late-stage biotechnology company advancing a potentially best-in-class, highly potent and selective next generation URAT1 ...

Courtney Southwick is a writer focusing on health, nutrition, and disease. She has been blogging for the past two years at CourtneySouthwick.com. She writes blogs and articles for online publications ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

GOUT - a condition which people commonly associate with a rich diet - is a disorder which causes painful attacks of arthritis in the joints of the foot, knee, ankle, hand and wrist and especially the ...