The requirement for Tie2 in VE-PTP dependent dephosphorylation of VEGFR2 was further demonstrated by silencing either VE-PTP or Tie2 in primary ECs using short interfering RNA (siRNA). Thus, i) ...
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emerging evidence suggests ...
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