在一项新的研究中，来自美国耶鲁大学的研究人员在活体小鼠体内构建出功能性“人源化（humanized）”肝脏，这将有助于科学家们找到调节胆固醇水平的人体特异性机制，并有可能治疗困 在一项新的研究中，来自美国耶鲁大学的研究人员在活体小鼠体内构建出 ...

Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic ...

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms? Researchers in the lab of Yale’s Richard Flavell decided to ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Immunotherapy harnesses a patient’s own immune system to combat cancer, with numerous benefits compared to conventional treatments such as chemotherapy and surgical removal. 1 Among different ...

Currently developed cancer immunotherapies modify the interaction of cancer cells and the immune system, making drug testing targeting human cancer outside of clinical trials difficult. Kobe ...

Every animal model of disease comes with its own unique set of drawbacks. Yet, scientists continually push to improve the quality of animal models to recapitulate the physiological and molecular ...

Mice carrying a "humanized version" of a gene believed to influence speech and language may not actually talk, but they nonetheless do have a lot to say about our evolutionary past, according to a new ...