The discovery of leptin in 1994 led to renewed interest in the hormonal regulation of energy balance. Leptin was discovered through positional cloning of the mouse obese (ob) gene; 1 homozygous ...

Could people with Type 1 diabetes one day replace insulin with leptin? A research team at UT Southwestern has had promising results with animal studies and now is laying the groundwork for testing it ...

DALLAS, Dec. 18 – Leptin, a protein secreted by fat cells, may be an independent risk factor for heart disease in humans, according to an article today in Circulation: Journal of the American Heart ...

Leptin, a protein secreted by fat cells, may be an independent risk factor for heart disease in humans, according to an article in Circulation: Journal of the American Heart Association. Leptin, a ...

Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...