Objective Systemic lupus erythematosus (SLE) is associated with increased susceptibility to infections, including herpes ...

Objectives To achieve consensus on domains of active disease for inclusion in a novel outcome measure for SLE randomised controlled trials (RCTs), the Treatment Response Measure for SLE (TRM-SLE).

Objectives This study aimed to evaluate the prevalence of specific autoantibodies in asymptomatic first-degree relatives of Systemic Lupus Erythematosus patients compared to healthy controls. Methods ...

Objectives Lupus nephritis (LN) is a major cause of morbidity in patients with systemic lupus erythematosus (SLE). B cells have a central role in the pathogenesis of SLE. B lymphocyte stimulator (BLyS ...

Our 2022 published working definition of disease modification in systemic lupus erythematosus (SLE) was ‘minimising disease activity with the fewest treatment-associated toxicities and slowing or ...

Background Cognitive dysfunction (CD) is highly prevalent in systemic lupus erythematosus (SLE), yet the underlying mechanisms are poorly understood. Neuroimaging utilising advanced MRI metrics may ...

Objectives Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), characterised by unpredictable outcomes due to the absence of reliable biomarkers. This study aimed to ...

Our purpose was to compile information on the haematological manifestations of systemic lupus erythematosus (SLE), namely leucopenia, lymphopenia, thrombocytopenia, autoimmune haemolytic anaemia (AIHA ...

Objectives SLE and APS are autoimmune disorders that may first manifest during pregnancy or the postpartum period, often mimicking obstetric complication such as preeclampsia. The aim of this case ...

Objectives Patients with systemic lupus erythematosus (SLE) have an increased risk of thrombosis driven by complex interactions between the innate immune system, autoantibodies, the coagulation ...

Objectives Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. Immune alterations often precede clinical onset, yet the molecular characteristics of this preclinical phase ...

Objectives This study aims to evaluate capillaroscopic abnormalities in systemic lupus erythematosus (SLE) patients versus healthy controls and to explore correlations between microvascular changes ...