Researchers found that psilocybin and MDMA may alleviate PTSD symptoms by promoting myelin remodeling in the brain. In rat models, psychedelic treatment triggered oligodendrocyte-driven myelin repair ...

Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks. New research shows that treatment with ...

Professor of Pathology, Lee J. Martin, discusses the prevalence and treatment challenges associated with hypoxic-ischemic encephalopathy (HIE) ...

This article and associated images are based on a poster originally authored by Sophie O’Neil, Kyle Thompson, Rita Pereira, Emily Russell and Stuart McElroy and presented at ELRIG Drug Discovery 2025 ...

Panic Disorder (PD) is a prevalent psychiatric condition characterized by recurrent episodes of acute severe anxiety. These episodes frequently present with symptoms that overlap with those of ...

Researchers at Mount Sinai have mapped how the 5-HT1A serotonin receptor controls brain signalling – finding a hidden lipid ‘co-pilot’ that could lead to the development of more targeted ...

Q: What did researchers discover about the serotonin 5-HT1A receptor? A: They mapped how it activates different brain signaling pathways, offering insight into how mood and emotion are regulated at ...

Provided herein are novel substituted lactams as 5-HT1A agonists, pharmaceutical compositions, use of such compounds in treating neuropsychiatric diseases and processes for preparing such compounds.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator.