Acetylcholine (ACh) is a neuromodulator with a central role in aversive learning - rapid conditioning to unpleasant smell, taste, or touch. These learning functions play out in cells called D2 ...

A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk ...

Researchers identify how acetylcholine sets off a signal cascade in brain cells that directly influence aversive learning and memory formation. Patients with Alzheimer's disease (AD) have lower levels ...

Scientists are reporting the first compelling evidence in people that cognitive training can boost levels of a brain chemical that typically declines with age. A 10-week study of people 65 or older ...

Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...