In preparation of an upcoming neoadjuvant study investigating iniparib in combination with various taxane-based chemotherapies, we have evaluated the prevalence of PARP expression in various subtypes ...

Background The inhibition of poly (adenosine diphosphate [ADP]–ribose) polymerase (PARP) is a potential synthetic lethal therapeutic strategy for the treatment of cancers with specific DNA-repair ...

Researchers at Gifu University’s Institute for Glyco-core Research have developed two synthetic approaches to produce a fragment of a molecule called poly(ADP-ribose). By developing two ways to ...

THE physiology of virus-infected plant tissues is of interest in that an understanding of the processes underlying the development of disease symptoms is dependent on a knowledge of changes in the ...

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