A recently described hemorrhagic disorder characterized by defective platelet aggregation induced by collagen and epinephrine appears to be caused, in part, by the same abnormality induced by aspirin ...

THE physiology of virus-infected plant tissues is of interest in that an understanding of the processes underlying the development of disease symptoms is dependent on a knowledge of changes in the ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

In preparation of an upcoming neoadjuvant study investigating iniparib in combination with various taxane-based chemotherapies, we have evaluated the prevalence of PARP expression in various subtypes ...

Background The inhibition of poly (adenosine diphosphate [ADP]–ribose) polymerase (PARP) is a potential synthetic lethal therapeutic strategy for the treatment of cancers with specific DNA-repair ...

Hypermetabolic activity by FDG-PET after immunogenic chemotherapy and multi-peptide immunotherapy in ovarian cancer. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract ...

Machines running on human energy? Yes, it can happen, according to Dan Nicolau, Jr. from the Department of Integrative Biology at the University of California. Nicolau and his colleagues successfully ...