Abstract: Bistability plays a key role in important biological processes, such as cell division, differentiation, and apoptosis. Examples show that there is a very delicate relationship between the ...

In developmental and pathological tissues, nascent vessel networks generated by angiogenesis require further pruning/regression to delete nonfunctional endothelial cells (ECs) by apoptosis and ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

Apoptosis is a form of programmed cell death that occurs in multicellular organisms and some eukaryotic microorganisms. Apoptosis is a series of biochemical events that lead to chromatin condensation ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, College of Animal Science and ...

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

Department of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung 407219, Taiwan R.O.C. Department of Physical Therapy, Hung Kuang ...

UPR-to-apoptosis transition is a tightly regulated process that involves coordination within subcellular compartments. Among these, ER dynamics, as the first place during UPR to apoptosis, plays a ...

Cells achieve cancer suppression through multiple mechanisms. It has been known that p53, the master regulator of cancer suppression, activates gene expression of RPRM, but how RPRM fulfills its role ...