Cancer biomarkers span a broad biological spectrum, including proteins, metabolites, and nucleic acids detectable in samples such as tissue biopsies and blood. 1 At the beginning of a biomarker ...

The landscape of dementia diagnostics is undergoing a paradigm shift with the emergence of liquid biopsy, blood-based biomarkers (BBMs), and blood-derived ...

Explore how proteomics in biomarker discovery accelerates diagnostic assay development and improves clinical validation.

In a recent editorial published in Current Pharmaceutical Analysis (Volume 18, Issue 6, 2022), researchers Dr. Behrouz Seyfinejad and Dr. Abolghasem Jouyban highlight the importance of method ...

However, regardless of which trial is conducted, the overfitting of data might be a substantial issue, meaning that the number of parameters in a model is too great relative to the number of samples, ...

The CHAI platform extracted quantitative histomorphologic features from whole-slide images of hematoxylin and eosin–stained diagnostic biopsies. In a multi-institutional development cohort, features ...

A multimodal artificial intelligence (MMAI)–derived predictive biomarker was trained for long-term (LT) versus short-term (ST) ADT using pretreatment digital prostate biopsy images and clinical data ...

This article explores multiplexing applications in biopharma and highlights key assay development factors to consider.

Background: The Prognostic Lung Fibrosis Consortium (PROLIFIC) was formed to develop well-qualified assays suitable for use as prognostic biomarkers within the context of clinical trials for Idiopathic ...

Autoimmune and autoinflammatory diseases are distinct but related categories of disorders characterized by an abnormal immune response. While autoimmune diseases involve adaptive immunity and the ...