A recent study shows that skeletal muscle responds to tumor-secreted factors by undergoing a change in fatty acid metabolism, and that blocking this metabolic response in mice inhibits muscle wasting.

A meta-analysis GWAS of taxane-induced peripheral neuropathy in patients with breast cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full ...

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body. This wasting syndrome, known as cachexia, ...

Cachexia is a condition which denotes the excessive loss of weight. It occurs because of the depletion of adipose tissue and muscle mass in people who are not trying to lose weight. It is also known ...

Cancer cachexia is a multifactorial syndrome characterized by skeletal muscle loss leading to progressive functional impairment. Despite the ubiquity of cachexia in clinical practice, prevention, ...

Rheumatoid arthritis (RA) can lead to a metabolic state called rheumatoid cachexia, or muscle wasting. This form of cachexia happens when your body loses muscle mass and keeps fat mass. Your body ...

Cachexia in older SCLC patients leads to inferior survival rates and increased treatment complications, such as dose reductions and incomplete chemotherapy courses. Patients with cachexia had ...

Maintaining good health and well-being is crucial for how well patients respond to cancer treatments. Unfortunately, cachexia, or involuntary weight loss, is a major concern for many individuals with ...

With cachexia, the muscles in your body will waste away regardless of how much you eat. The condition causes severe weight loss. (Photo Credit: Dr P. Marazzi/Science Source) Cachexia (aka “wasting ...

Rheumatoid cachexia, or muscle wasting, is a common complication of rheumatoid arthritis (RA) that can lead to fatigue, pain, and even a shorter life expectancy if left unmanaged. While the exact ...

New research from the University of Oklahoma, published today in Cancer Cell, describes for the first time a "triangle regulation theory" of cancer-induced cachexia and anorexia. Cachexia is a ...