Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

PI3K/AKT/mTOR pathway blockade with pan-PI3K/mTORC1/2 inhibition produced substantial PFS gains in PIK3CA wild-type disease, addressing an unmet need after CDK4/6 plus endocrine resistance. Adding ...

Prostate cancer screening saves many more lives than earlier studies suggested, research shows. The results from the longest-running European trial show one life saved for every six men diagnosed, a ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Researchers at NYU Langone Health have detected tiny plastic fragments in nine out of 10 prostate cancer tumors examined, a ...

In this interview, Sagar Lonial, MD, discussed the EXCALIBER-RRMM trial design and the potential role of iberdomide in the ...

In a study of adults with advanced prostate cancer taking androgen-receptor pathway inhibitors and different types of ...

A leading oncologist reveals science-backed foods that may help lower cancer risk, highlighting how a plant-forward, fiber-rich diet can reduce inflammation and support long-term health.

In the realm of cellular biology, programmed cell death (PCD) stands as a pivotal process governing the elimination of cells, thereby maintaining tissue homeostasis and ensuring an organism's health ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, ...

A systemwide collaborative integrates palliative care, EHR-based patient flagging, and cross-disciplinary support to address the psychosocial and clinical risks that often derail cancer treatment.