Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

DNA MRD monitoring offers new clues for stopping chemo safely in metastatic gastroesophageal cancer, linking molecular response to outcomes. In an interview with Targeted Oncology, Rutika Mehta, MD, ...

PI3K/AKT/mTOR pathway blockade with pan-PI3K/mTORC1/2 inhibition produced substantial PFS gains in PIK3CA wild-type disease, addressing an unmet need after CDK4/6 plus endocrine resistance. Adding ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

The long-term stasis of blood in the liver, known as chronic liver congestion, can lead to a range of diseases, some of which ...

Researchers at NYU Langone Health have detected tiny plastic fragments in nine out of 10 prostate cancer tumors examined, a ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

A leading oncologist reveals science-backed foods that may help lower cancer risk, highlighting how a plant-forward, fiber-rich diet can reduce inflammation and support long-term health.

In the realm of cellular biology, programmed cell death (PCD) stands as a pivotal process governing the elimination of cells, thereby maintaining tissue homeostasis and ensuring an organism's health ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.