The activated leukocyte cell adhesion molecule (ALCAM) is a critical member of the immunoglobulin superfamily that mediates both homotypic and heterotypic cell interactions. It plays a central role in ...

AMES, Iowa – Sanjeevi Sivasankar knows a lot about how the healthy cells in your body stick together. He and his research team have studied cell adhesion proteins called cadherins. They’ve developed ...

Cancer remains one of the world’s most serious health threats, especially when it spreads beyond its original site. That ...

Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

High-grade serous ovarian cancer is the most common and aggressive form of ovarian cancer and often becomes resistant to ...

Scientists at Duke-NUS Medical School have identified a molecular "switch" that determines whether pancreatic cancer cells resist chemotherapy or respond to it—a finding that could help convert some ...

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...

A new study led by researchers at Adelaide University and published in Science Advances reveals why some cancers can grow and survive in the body, while others cannot. It turns out that intense ...

A guardian molecule ensures that liver cells do not lose their identity. The discovery is of great interest for cancer medicine because a change of identity of cells has come into focus as a ...